Treatment of Neuromyelitis Optica: Review and Recommendations

In this category you will have access to a database containing journal articles in the form of abstracts and full journal articles.
Post Reply
Ashlee
Site Admin
Site Admin
Posts: 62
Joined: Fri Sep 01, 2017 10:28 pm

Treatment of Neuromyelitis Optica: Review and Recommendations

Post by Ashlee » Tue Aug 28, 2018 4:40 pm

Dorlan J Kimbrough, MD, Kazuo Fujihara, MD, [...], and GJCF-

Neuromyelitis optica (NMO) is an autoimmune demyelinating disease preferentially targeting the optic nerves and spinal cord. Once regarded as a variant of multiple sclerosis (MS), NMO is now recognized to be a different disease with unique pathology and immunopathogenesis that does not respond to traditional MS immunomodulators such as interferons. Preventive therapy in NMO has focused on a range of immunosuppressive medications, none of which have been validated in a rigorous randomized trial. However, multiple retrospective and a few recent prospective studies have provided evidence for the use of six medications for the prevention of NMO exacerbations: azathioprine, rituximab, mycophenolate mofetil, prednisone, methotrexate and mitoxantrone. This review provides a comprehensive analysis of each of these medications in NMO and concludes with a set of recommended consensus practices.

Continued Source at:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926208/
Site Admin Ashlee 💚

Post Reply

Return to “NMO Library”