Why MOG Antibody Disease May or May Not Be Part of the Neuromyelitis Optica Spectrum

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Ashlee
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Why MOG Antibody Disease May or May Not Be Part of the Neuromyelitis Optica Spectrum

Post by Ashlee » Mon Feb 26, 2018 1:47 pm

BY ED SUSMAN

PARIS—Should myelin oligodendrocyte glycoprotein (MOG) antibody disease, which causes brain inflammation, be no longer considered a disorder in the neuromyelitis optica (NMO) spectrum? Experts debated the question here at the joint meeting of the European Committee for Treatment and Research in Multiple Sclerosis and the Americas Committee for Treatment and Research in Multiple Sclerosis. When the dust had settled, the co-moderators declared that the answer was "yes."

Douglas Sato, MD, PhD, professor of neurology at the Brain Institute of the Rio Grande do Sul in Porte Allegre, Brazil, contended that there were enough differences between patients whose brain inflammatory disease is caused by MOG antibodies to make it a separate disorder.

He noted that 161 citations supported his thesis in reports from cohorts in the United Kingdom, Switzerland, Austria, Japan, South Korea, India, Australia, France, and other countries. The studies noted distinct differences between MOG antibody diseases and aquaporin-4 antibody diseases that are hallmarks of NMO spectrum disorders

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https://journals.lww.com/neurotodayonli ... ?PostID=27
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