Search found 60 matches
- Mon Apr 16, 2018 9:01 pm
- Forum: Forum: Anti-Mog
- Topic: MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, pre
- Replies: 0
- Views: 14276
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, pre
Sven Jarius, Ingo Kleiter, [...], and in cooperation with the Neuromyelitis Optica Study Group (NEMOS) Additional article information Abstract Background Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) are present in a subset of aquaporin-4 (AQP4)-IgG-negative patients with optic neuritis (...
- Fri Apr 13, 2018 9:00 pm
- Forum: What is NMO
- Topic: Q & A about NMO with Brian Weinshenker, M.D.
- Replies: 0
- Views: 22054
Q & A about NMO with Brian Weinshenker, M.D.
What are early warning signs that an NMO attack is imminent? BW: The major symptoms of NMO are optic neuritis and transverse myelitis. Optic neuritis causes eye pain and blurring of vision or blank spots in the field of vision, typically in one eye at a time, but occasionally in both simultaneously....
- Tue Apr 03, 2018 9:51 pm
- Forum: Clinical Research
- Topic: pen-label, add-on trial of cetirizine for neuromyelitis optica
- Replies: 0
- Views: 16757
pen-label, add-on trial of cetirizine for neuromyelitis optica
Abstract Objective This pilot study preliminarily examined the efficacy and tolerability of cetirizine as an add-on to standard therapy for neuromyelitis optica (NMO). Methods Eligible participants met the Wingerchuk 2006 diagnostic criteria or had a single typical episode along with positive NMO im...
- Tue Apr 03, 2018 9:30 pm
- Forum: Forum: Anti-Mog
- Topic: Clinical presentation and prognosis in MOG-antibody disease: a UK study
- Replies: 0
- Views: 14613
Clinical presentation and prognosis in MOG-antibody disease: a UK study
Abstract See de Seze (doi:10.1093/brain/awx292) for a scientific commentary on this article. A condition associated with an autoantibody against MOG has been recently recognized as a new inflammatory disease of the central nervous system, but the disease course and disability outcomes are largely un...
- Fri Mar 23, 2018 7:10 pm
- Forum: Imuran (Azathioprine)
- Topic: Long-term efficacy, tolerability and retention rate of azathioprine in 103 aquaporin-4 antibody-positive
- Replies: 0
- Views: 21563
Long-term efficacy, tolerability and retention rate of azathioprine in 103 aquaporin-4 antibody-positive
Long-term efficacy,tolerability and retention rate of azathioprine in 103 aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder patients: a multicentre retrospective observational study from the UK Liene Elsone1, Joanna Kitley2, Sebastian Luppe3, Daniel Lythgoe4, Kerry Mutch1, Saiju J...
- Thu Mar 15, 2018 10:58 pm
- Forum: Clinical Research
- Topic: Restoring immune tolerance in neuromyelitis optica: Part I.
- Replies: 0
- Views: 14369
Restoring immune tolerance in neuromyelitis optica: Part I.
Abstract Neuromyelitis optica (NMO) and spectrum disorder (NMO/SD) represent a vexing process and its clinical variants appear to have at their pathogenic core the loss of immune tolerance to the aquaporin-4 water channel protein. This process results in a characteristic pattern of astrocyte dysfunc...
- Thu Mar 15, 2018 10:50 pm
- Forum: Clinical Research
- Topic: Restoring immune tolerance in neuromyelitis optica: Part II.
- Replies: 0
- Views: 14217
Restoring immune tolerance in neuromyelitis optica: Part II.
Abstract Neuromyelitis optica spectrum disorder (NMO/SD) and its clinical variants have at their core the loss of immune tolerance to aquaporin-4 and perhaps other autoantigens. The characteristic phenotype is disruption of astrocyte function and demyelination of spinal cord, optic nerves, and parti...
- Thu Mar 15, 2018 12:08 pm
- Forum: Effectiveness and safety of immunosuppressive therapy in neuromyelitis optica spectrum disorder during pregnancy.
- Topic: Rituximab before and during pregnancyA systematic review, and a case series in MS and NMOSD
- Replies: 0
- Views: 16069
Rituximab before and during pregnancyA systematic review, and a case series in MS and NMOSD
Abstract Objective To evaluate the safety of rituximab treatment before and during pregnancy in women with MS and neuromyelitis optica spectrum disorders (NMOSDs) who may be at risk of relapses by performing a systematic literature review combined with a retrospective single-center case series. Meth...
- Wed Mar 14, 2018 11:37 pm
- Forum: Effectiveness and safety of immunosuppressive therapy in neuromyelitis optica spectrum disorder during pregnancy.
- Topic: Takeing Imuran and/or prednisone while being pregnant
- Replies: 0
- Views: 5966
Takeing Imuran and/or prednisone while being pregnant
Abstract OBJECTIVE: To evaluate the effectiveness and safety of immunosuppressive therapy in neuromyelitis optica spectrum disorder (NMOSD) during pregnancy. METHODS: Sixteen NMOSD patients who had at least one pregnancy after NMOSD onset were enrolled. The patients were divided into two groups acco...
- Thu Mar 01, 2018 9:03 am
- Forum: Forum: Share your Story
- Topic: A Modern Medical Miracle
- Replies: 5
- Views: 10420
Re: A Modern Medical Miracle
Your story is truly amazing and an inspiration to all.